Conclusions: The framework enabled the sensitivity of a prostate cancer screening round relative to histological cancer diagnosis to be estimated and provides a basis to determine the impact and cost-effectiveness of prostate cancer screening.

PSE Has 'Remarkable' Accuracy. Results showed an overall accuracy for EpiSwitch of 94% - vastly superior to PSA testing alone. PSA alone at a cut-off of >3 ng/mL showed a low positive predicted value (PPV) of 0.14 and a high negative predicted value (NPV) of 0.93. In contrast, EpiSwitch alone showed a PPV of 0.91 and an NPV of 0.32.

Prostate-specific antigen (PSA) screening reduces prostate cancer (PCa) mortality; however such screening may lead to harm in terms of overdiagnosis and overtreatment. Although organized screening with the blood test prostate-specific antigen (PSA) (with different thresholds) had significantly higher sensitivity than the strategy with
Using a total PSA cut-off value of 4 ng/ml, the sensitivity of the Sangia Total PSA Test was 85.4% (95% CI 80.3-89.4%), and when combined with DRE the sensitivity increased to 91.0% (95% CI 86.6
Background Although prostate-specific antigen (PSA) is widely used in prostate cancer (PCa) screening, nearly half of PCa cases are missed and less than one-third of cases are non-lethal. Adopting diagnostic criteria in population-based screening and ignoring PSA progression are presumed leading causes. Methods A total of 31,942 participants with multi-round PSA tests from the PLCO trial were
\n\n \n \n sensitivity of psa test for prostate cancer
Detecting the presence of prostate cancer (PCa) and distinguishing low- or intermediate-risk disease from high-risk disease early, and without the need for potentially unnecessary invasive biopsies remains a significant clinical challenge. The aim of this study is to determine whether the T and B cell phenotypic features which we have previously identified as being able to distinguish between ucgUW5.
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    • sensitivity of psa test for prostate cancer